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However, compared to standard treatment or other forms of treatment, the combination was associated with significant reductions in these outcomes

Exp Neurol 231:171180 Lefort N, Glancy B, Bowen B, Willis WT, Bailowitz Z et al (2010) Increased reactive oxygen species production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin-resistant human skeletal muscle

Those looking to lose a few pounds would be better served with non-medical interventions

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